Bold Creamy Cajun Chicken Pasta

Featured in: One-Pot Family Comfort Meals

This dish features tender strips of chicken seasoned with bold Cajun spices, combined with sautéed red and yellow bell peppers and red onion. A silky garlicky cream sauce enriched with Parmesan cheese binds the flavors together, coating the pasta perfectly for a hearty, comforting meal. Quick to prepare, it balances spice with creamy richness, making it ideal for an inviting weeknight dinner.

The method involves cooking pasta al dente, browning Cajun-spiced chicken, and gently softening vegetables before simmering them all in a luscious butter and cream base. Adding reserved pasta water helps achieve a smooth, clingy sauce. Garnishing with chopped fresh parsley and extra Parmesan adds fresh and savory finishing touches.

Updated on Wed, 24 Dec 2025 16:53:00 GMT
Cajun Chicken Pasta with a creamy, rich sauce, topped with fresh parsley and Parmesan. Save
Cajun Chicken Pasta with a creamy, rich sauce, topped with fresh parsley and Parmesan. | wheatkettle.com

There's something about the smell of Cajun spices hitting hot oil that makes everything else fade away. My cousin brought a container of this pasta to a potluck years ago, and I watched people go back for thirds without hesitation. I finally asked for the recipe, expecting something complicated, but it was wonderfully straightforward—just good chicken, cream, and enough flavor to make you forget you're eating something so simple. Now it's the dish I make when I want to feel like I'm cooking something special without the stress.

I made this for my roommate on a random Thursday when she'd had a rough day at work. She took one bite and just closed her eyes—not in a critical way, but in that relieved, comforted way food sometimes hits. That's when I knew this recipe was worth keeping close.

Ingredients

  • Boneless, skinless chicken breasts: Slice them thin so they cook through quickly and stay tender; thick pieces turn tough before the centers are done.
  • Cajun seasoning: This is your backbone, so don't skimp or water it down with extra salt—it should coat the chicken visibly.
  • Olive oil: Medium heat is your friend here; hot oil will burn the spices before the chicken finishes.
  • Penne or fettuccine: Either works, but penne catches the sauce better in every bite.
  • Red and yellow bell peppers: The color matters as much as the taste—they brighten the whole dish and soften into the sauce beautifully.
  • Red onion: It stays slightly sweet and adds a gentle bite that balances the richness.
  • Garlic: Mince it fine so it disappears into the sauce rather than sitting in chunks.
  • Unsalted butter: It's your canvas for building the sauce base without guessing salt levels later.
  • Heavy cream: The real thing, not half-and-half—it makes the sauce coat the pasta properly.
  • Chicken broth: Keeps the sauce from becoming too heavy and adds subtle depth.
  • Parmesan cheese: Freshly grated melts smoothly; pre-grated versions have anti-caking agents that create graininess.

Instructions

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Start the pasta:
Bring a big pot of salted water to a rolling boil and add your pasta, stirring once so nothing sticks. You want al dente, so start checking a minute or two before the box says—it should have a slight resistance when you bite it.
Season the chicken:
Toss your chicken strips in the Cajun seasoning while you wait for the pasta water to boil. This gives the spices a moment to cling to the meat rather than falling off in the pan.
Sear the chicken:
Heat olive oil in a large skillet over medium-high heat until it shimmers slightly, then add the chicken in a single layer. Don't move it around for the first couple of minutes—let it brown and develop flavor before flipping.
Build the base:
Once the chicken is golden and cooked through, remove it to a plate and melt butter in the same skillet. The fond (those browned bits) is liquid gold for flavor, so keep scraping as you cook the peppers, onion, and garlic.
Create the sauce:
Pour in the cream and broth, stirring constantly so the flavors blend smoothly. You'll see the sauce thicken slightly as it simmers—that's your cue it's ready for the cheese.
Finish with cheese:
Lower the heat to prevent the cream from breaking and stir in the Parmesan slowly, letting each handful melt before adding more. Taste here and season with salt and pepper—this is your last chance to adjust.
Bring it together:
Add the drained pasta back to the pot along with the chicken and a splash of reserved pasta water. The starch in that water helps the sauce cling to every strand, so don't skip it.
Finish and serve:
Toss everything gently so the sauce coats evenly, then plate it immediately while it's still hot and creamy. Top with fresh parsley and a scatter of extra Parmesan.
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Tender Cajun Chicken Pasta with colorful bell peppers in a garlic-infused cream sauce delight. Save
Tender Cajun Chicken Pasta with colorful bell peppers in a garlic-infused cream sauce delight. | wheatkettle.com

Someone once told me that the best comfort food is the kind that makes you feel taken care of, and this pasta does exactly that. It's bold enough to feel special but gentle enough to wrap around you like a warm blanket.

Why Cajun Flavors Work So Well Here

Cajun spices are built to be social—they're warm, layered, and unapologetic, which is exactly what a cream sauce needs to shine. Unlike delicate herbs that fade, these spices actually get better when they meet fat; the cream doesn't dilute them, it amplifies them. That's why this dish feels so much more interesting than basic chicken pasta, even though the core ingredients are exactly the same.

The Pasta Water Magic

The starch in reserved pasta water is one of those kitchen secrets that feels almost too simple to matter, but it genuinely transforms the whole dish. Instead of sauce that slides to the bottom of your bowl, you get something that clings and coats, turning ordinary penne into something that tastes intentional. It's the difference between a sauce and a complete bite.

Making It Your Own

This recipe is a canvas, not a mandate, so don't be afraid to play with it. Add a handful of spinach while the sauce simmers, or swap the chicken for shrimp if you're in the mood for something brighter. Even small changes let you make it feel like your own discovery.

  • For extra heat, add a pinch of cayenne pepper or smoked paprika to the cream base.
  • If you have fresh thyme or basil on hand, a light toss at the end brings a fresh brightness that cuts through the richness.
  • Mushrooms sautéed with the peppers add an earthy depth that some people swear makes it even better.
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A steaming bowl of flavorful Cajun Chicken Pasta, ready to savor for dinner tonight. Save
A steaming bowl of flavorful Cajun Chicken Pasta, ready to savor for dinner tonight. | wheatkettle.com

This is the kind of dish that quietly becomes a regular in your rotation, the one people ask you to make again and again. There's real pleasure in that.

Common Recipe Questions

Can I substitute the chicken with another protein?

Yes, shrimp can be used as a flavorful alternative for a seafood variation, adapting well to the creamy Cajun sauce.

How can I add extra heat to the dish?

Including a pinch of cayenne pepper or using a spicier Cajun seasoning blend will enhance the heat level without overpowering the flavors.

What type of pasta works best with this dish?

Penne or fettuccine both hold the creamy sauce well, but any pasta shape that captures sauce can be used according to preference.

Can I make this dish dairy-free?

To make it dairy-free, substitute butter and heavy cream with vegan alternatives and omit Parmesan or use a dairy-free cheese substitute.

What is the purpose of reserving pasta water?

The reserved pasta water adds starch that helps emulsify and thicken the sauce, creating a smooth and clingy texture.

How do I prevent the chicken from drying out?

Cook the chicken strips over medium-high heat just until browned and cooked through, avoiding overcooking to keep them tender.

Bold Creamy Cajun Chicken Pasta

Tender chicken and sautéed peppers in a creamy, garlicky Cajun-inspired pasta sauce.

Prep Duration
15 minutes
Cook Duration
25 minutes
Overall Time
40 minutes
Created by Lillian Roberts


Skill Level Medium

Cuisine Type American (Cajun-inspired)

Makes 4 Portions

Diet Info None specified

What You Need

Chicken

01 2 large boneless, skinless chicken breasts (approximately 16 oz), sliced into strips
02 1 ½ tablespoons Cajun seasoning
03 1 tablespoon olive oil

Pasta

01 12 oz penne or fettuccine pasta

Vegetables

01 1 red bell pepper, thinly sliced
02 1 yellow bell pepper, thinly sliced
03 1 small red onion, thinly sliced
04 2 cloves garlic, minced

Sauce

01 2 tablespoons unsalted butter
02 1 cup heavy cream
03 ¼ cup chicken broth
04 ½ cup freshly grated Parmesan cheese
05 Salt and black pepper, to taste

Garnish

01 Fresh parsley, chopped
02 Extra Parmesan cheese

Steps

Step 01

Cook Pasta: Boil pasta in a large pot of salted water until al dente. Drain, reserving ¼ cup pasta water. Set pasta aside.

Step 02

Season Chicken: Coat chicken strips evenly with Cajun seasoning.

Step 03

Sauté Chicken: Heat olive oil in a large skillet over medium-high heat. Add chicken and cook for 5 to 7 minutes until browned and cooked through. Remove from skillet and set aside.

Step 04

Cook Vegetables: Melt butter in the same skillet over medium heat. Add bell peppers, red onion, and garlic. Sauté for 4 to 5 minutes until vegetables soften.

Step 05

Prepare Sauce: Pour in heavy cream and chicken broth, scraping up browned bits from the skillet. Simmer for 2 to 3 minutes until sauce thickens slightly.

Step 06

Add Cheese and Season: Reduce heat to low and stir in Parmesan until melted and sauce is creamy. Season with salt and black pepper to taste.

Step 07

Combine Pasta and Chicken: Return cooked pasta and chicken to the skillet along with reserved pasta water. Toss to thoroughly coat and heat through.

Step 08

Serve: Plate immediately and garnish with chopped fresh parsley and additional Parmesan cheese.

Essential Gear

  • Large pot
  • Large skillet
  • Chef's knife
  • Cutting board
  • Colander

Allergy Notice

Read each ingredient label for allergens and talk to a professional if you're unsure.
  • Contains dairy (cream, butter, Parmesan) and wheat (pasta).
  • May contain sulfites present in some Cajun seasoning blends.

Nutrition Details (per serving)

Details here are for general info and aren't meant as medical advice.
  • Kcal: 610
  • Fats: 26 grams
  • Carbohydrates: 56 grams
  • Proteins: 36 grams